Medicare Provider Enrollment: Complete 2025 Guide for Solo Practitioners
- Published: August 21, 2025

Becoming a Medicare provider is essential for solo practitioners who want to serve the growing population of Medicare beneficiaries and ensure timely reimbursement. This guide from Alpha Core Healthcare outlines each step of the Medicare provider enrollment process for 2025, highlights documents you’ll need, and answers common questions.
- Why Enroll as a Medicare Provider?
Medicare is America’s largest health insurer, with millions of covered beneficiaries. When you join, you position your practice for stability, growth, and increased patient access.
- Step 1: Obtain Your NPI (National Provider Identifier)
- What is NPI?
NPI stands for National Provider Identifier, a 10-digit unique identifier for healthcare providers. All Medicare providers, whether they practice independently or not, require one.
- Where to Get It?
Apply online at the [National Plan and Provider Enumeration System (NPPES)].
- Step 2: Secure Required Documents
Having your documents ready in advance streamlines the process:
- Current, not temporary, state medical license
- NPI verification
- Professional liability insurance evidence
- Current CV or resume
- Education and training records
- DEA/Controlled Substance Registration (if applicable)
- IRS forms for your Tax ID (if billing as an entity)
- Step 3: Complete the Medicare Enrollment Application (PECOS/CMS-855I)
- Application Portal:
The majority of providers use the PECOS online platform. You can also complete the CMS-855I paper application.
- Form Selection:
- Solo practitioners/individuals: File CMS-855I
- If billing through an entity: You may also be required CMS-855B
- Tips:
Double–check all entries and attachments. Incomplete forms delay #1.
- Step 4: Work with Your Medicare Administrative Contractor (MAC)
- Your Medicare application will be processed by your local MAC.
- Be responsive! If the MAC requests clarification, respond within 30 days or risk delay.
- MACs can request site visits or additional documents.
- Step 5: Application Processing & Receiving Your PTAN
- Processing Time:
- 45–60 days on average; can extend to 120 days during peak periods.
- Approval:
- Once approved, you’ll receive your Provider Transaction Access Number (PTAN) – use this to bill Medicare.
- Step 6: Ongoing Compliance & Maintaining Enrollment
- Keep info up to date:
- Report address, ownership, or major status changes within 30 days, all other changes within 90 days.
- Regular revalidation:
- CMS may request periodic revalidation of your credentials.
Most Critical Tips for Smooth Enrollment
- Collect all necessary documents prior to starting your application.
- Use PECOS for easier tracking and status reporting.
- Reply to MAC correspondence promptly.
- Review CMS and MAC bulletins for regulatory updates.
Most Common Asked Questions
How long does a solo practitioner Medicare enrollment process take?
Plan ahead for 45–120 days, relying on the completeness of your application and MAC workload.
What happens if my application gets denied?
You can appeal or correct and resubmit. The MAC will give you reasons and instructions.
Can I bill Medicare before approval?
No, wait until you receive your PTAN and approval notice.
Need Help?
Alpha Core Healthcare offers provider credentialing assistance. Let us talk for consultation, document audits, or a hassle-free Medicare enrollment in 2025.
By pursuing these actions and adhering to best practices, solo practitioners can successfully enroll as Medicare providers and build a sound foundation for delivering services to Medicare beneficiaries.
Connect With Us
Have questions about credentialing, enrollments, or healthcare management? Our team is here to help.
- (302) 304-8686
- hello@alphacorehealthcare.com
- 3524 Silverside Rd, Wilmington, DE 19810, United States
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